Polycyclic triazoles used to inhibit allergic responses

Details Polycyclic triazoles used to inhibit allergic responses Polycyclic triazoles used to inhibit allergic responses

1978-10-23

1981-04-21

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548259, A61K 3141, C07D24900

Patent

active

042633095

ABSTRACT:
Compounds of formula (I): ##STR1## and pharmaceutically acceptable salts thereof wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 which may be the same or different, represent hydrogen, halogen, nitro, lower alkyl, or lower alkoxy, or any adjacent two of R.sub.1 to R.sub.4 taken together represent an alkylene group containing from 3 to 5 carbon atoms or a 1,4-buta-1,3-dienylene group are disclosed together with a method for their preparation. The compounds are useful as anti-allergic agents. With the exception of 4,9-dioxo-1H-naphtho-[2,3-d]-triazole, and its salts, all compounds of formula (I) are novel.

REFERENCES:
patent: 2879274 (1959-03-01), Scalera et al.
patent: 3198795 (1965-08-01), Lindsay et al.
patent: 3294812 (1966-12-01), Mosby

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