Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Patent
1995-06-07
1997-11-11
Chan, Christina Y.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
435 7021, 4351722, 530326, 53038885, 5303891, C07K 708, C07K 1628, C12P 2108
Patent
active
056860730
ABSTRACT:
Disclosed are methods for the preparation of polyclonal and monoclonal antibodies which bind specifically to a 43 kDa dystrophin-associated. The molecular weight of the 43 kDa protein is determined by electrophoretic separation under denaturing conditions, followed by transfer to a solid support and staining with wheat germ agglutinin. The method includes a step in which the peptide PKNMTPYRSPPPYVP (SEQ ID NO: 15) is administered to stimulate an immune response. Also disclosed are polyclonal and monoclonal antibodies which bind specifically to the 43 kDa dystrophin-associated protein.
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Campbell Kevin P.
Ervasti James M.
Ibraghimov Oxana B.
Leveille Cynthia J.
Chan Christina Y.
Farrell Kevin M.
The University of Iowa Research Foundation
Vander Vegt F. Pierre
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