Polychelant compounds

Details Polychelant compounds Polychelant compounds

1990-01-19

1994-01-25

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540474, 530405, 536 171, 536 174, 536 179, 930 25, C07D25702, C07H 2300, C07H 1512, C07H 1902

Patent

active

052817040

ABSTRACT:
There are disclosed polychelant compounds, that is multi-site metal chelating agents, and chelates formed therewith. The polychelants and especially their paramagnetic metal, heavy metal or radioactive metal polychelates are particularly suitable for use in diagnostic imaging, heavy metal detoxification or radiotherapy. The polychelants have a linear or branched oligomeric structure comprising alternating chelant and linker moieties bound together by amide or ester moieties the carbonyl groups whereof being adjacent the chelant moieties, each polychelant comprising at least two said chelant moieties capable of complexing a metal ion.

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Konings et al, Inorg. Chem. 1990 29, 1488-1491.

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