Polycatecholamide chelating agents

Details Polycatecholamide chelating agents Polycatecholamide chelating agents

1981-08-24

1984-04-10

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

564154, 564157, 564158, 424308, 424309, 424324, C07C10172

Patent

active

044423055

ABSTRACT:
Novel polybenzamide compounds useful for in vitro or in vivo chelation are described. The compounds have the formula ##STR1## Polyamines are reacted with 2,3-dimethoxy benzoyl chloride unsubstituted or substituted with SO.sub.3 H, SO.sub.3 M, NO.sub.2, CO.sub.2 H or CO.sub.2 M as desired is reacted with a polyamine in an inert solvent then demethylated with BBr.sub.3 or BCl.sub.3 in an inert solvent. Where compounds symmetrically substituted on the terminal N's are desired, the polyamine is first reductively alkylated by reaction with an aldehyde or ketone and the resulting Schiff base is hydrogenated.

REFERENCES:
patent: 3022268 (1962-02-01), Armitage
patent: 3869443 (1975-03-01), Lesher
patent: 4181654 (1980-01-01), Weitl
J. L. Corbin et al., Biochemistry 8, 757-762, (1969).
G. H. Tait, Biochem. J. 146, 191, (1975).

Affiliated with

Also associated with

Rating

Polycatecholamide chelating agents does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polycatecholamide chelating agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polycatecholamide chelating agents will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-894251