Polycarbonate membranes and production thereof

Liquid purification or separation – Filter – Material

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210 22D, 264 41, 264216, B01D 3916, B29D 2704

Patent

active

040751082

ABSTRACT:
Polycarbonate membranes useful for hemodialysis are fabricated from polyether-polycarbonate block copolymers by a water gelation process. The process comprises casting onto a substrate surface a layer of a multicomponent casting solution comprising the copolymer dissolved in a water-miscible organic solvent together with a cosolvent which acts as a swelling agent for the copolymer, drying the layer to partially evaporate the solvents therefrom, immersing the partially dried layer in water to form a gelled membrane, and stripping the gelled membrane from the substrate surface. The membrane has improved strength and improved permeability to solutes in the "middle molecule" range while maintaining clinically acceptable ultrafiltration rates and clearance of low molecular weight solutes.

REFERENCES:
patent: 3133132 (1964-05-01), Loeb et al.
patent: 3332894 (1967-07-01), Cantor et al.
patent: 3767737 (1973-10-01), Lundstrom
Goldberg, Eugene P., Journal of Polymer Science, part C, No. 4, pp. 707-730, (1963).
U.S. Department of Health, Education and Welfare, "Proceedings of the 5th Annual Contractor's Conference of the National Institute of Arthritis and Metabolic Diseases," (1972), pp. 32-33.
Billmeyer, Fred W., "Textbook of Polymer Science", New York, Interscience, .COPYRGT.1962, pp. 79-86.

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