Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1993-05-04
1994-05-24
Hollinden, Gary E.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
436173, 1286534, 534 15, 534 16, 540465, 540474, 514184, 514836, A61B 5055, C07D25502
Patent
active
053146808
ABSTRACT:
Novel magnetic resonance imaging agents comprise complexes of paramagnetic ions with hydrazide derivatives of polyaminocarboxylic acid chelating agents. These novel imaging agents are characterized by excellent NMR image-contrasting properties and by high solubilities in physiological solutions.
A novel method of performing an NMR diagnostic procedure involves administering to a warm-blooded animal an effective amount of a complex as described above and then exposing the warm-blooded animal to an NMR imaging procedure, thereby imaging at least a portion of the body of the warm-blooded animal.
REFERENCES:
patent: 4061642 (1977-12-01), Fleckenstein et al.
patent: 4478959 (1984-10-01), Bechara et al.
patent: 4647447 (1987-03-01), Gries et al.
patent: 4687658 (1987-08-01), Quay
patent: 4687659 (1987-08-01), Quay
patent: 4826673 (1989-05-01), Dean et al.
Himmelsbach, R. J. Chem. Abs. 119(11): 117286q (1993).
Turowski, P. N. et al. Inorganic Chemistry 27(3): 474-481 (1988).
Periasamy Muthunadar P.
Rajagopalan Raghavan
Wallace Rebecca A.
Hollinden Gary E.
Mallinckrodt Medical Inc.
Stierwalt Brian K.
LandOfFree
Polyazamacrocycles for magnetic resonance imaging does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polyazamacrocycles for magnetic resonance imaging, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polyazamacrocycles for magnetic resonance imaging will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1971315