Polyarenes from aryl ketones with application to synthesis of cr

Details Polyarenes from aryl ketones with application to synthesis of cr Polyarenes from aryl ketones with application to synthesis of cr

1997-12-22

1998-10-13

Burn, Brian M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564360, 568328, 585642, 585656, C07C20910

Patent

active

058213872

ABSTRACT:
Alkyl-substituted polyarenes of the formula ##STR1## in which R is alkyl and Ar.sub.res is an aryl residue, are prepared from aryl ketones by reaction of the latter with 1-cyclohexenyloxytrimethylsilane in the presence of a Friedel-Crafts catalyst. When R is methyl and Ar.sub.res is a naphthyl residue, the reaction serves as a step in a reaction scheme leading to crisnatol mesylate, a pharmaceutical useful in the treatment of brain cancer.

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