Polyanion for improved nucleic acid amplification

Details Polyanion for improved nucleic acid amplification Polyanion for improved nucleic acid amplification

2011-03-22

2011-03-22

Riley, Jezia (Department: 1637)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023100, C536S024300, C435S006120, C435S091100, C435S091200, C422S067000

Reexamination Certificate

active

07910720

ABSTRACT:
The present invention is directed to a novel chemical compound comprising the structure [Xx-(CH2)m-phosphate-Yy]n, characterized in that 3≦m≦6, 30≦n≦60, each x and y is independently from each other 0 or 1, each X and Y is independently from each other any photometrically measurable entity; provided that the terminal X can also be an —OH group or a phosphate group, and further provided that the terminal Y can also be an —OH group. Such a compound can be used as a suitable hot start additive for PCR based amplification of nucleic acids.

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