Polyaminic resin for the selective separation of heparin from ot

Liquid purification or separation – Processes – Ion exchange or selective sorption

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127 462, C13D 314

Patent

active

044117965

ABSTRACT:
A novel polyaminic resin obtained by crosslinking a polyalkyleneamine (in particular polyethyleneamine) with diisocyanates in solution, is useful as a selective separation or extraction agent of a component having a "complementary" chemical structure (particularly heparin), by means of mere contact or "ionic exchange" with aqueous solutions containing it. Heparin is thus even quantitatively extracted from solutions containing it alone or in mixture with other glucosaminoglycanes. The polyamine can then release the "adsorbed" heparin and be recovered by a treatment with saline solutions. The novel resin is used in pharmaco-biological fields.

REFERENCES:
patent: 3210299 (1965-10-01), Hagge et al.
patent: 3997483 (1976-12-01), Wurster et al.

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