Polyamine-polyamine and polyamine-protein transport inhibitor co

Details Polyamine-polyamine and polyamine-protein transport inhibitor co Polyamine-polyamine and polyamine-protein transport inhibitor co

1994-03-01

1995-10-10

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

424486, A61K 3174, A61K 31785

Patent

active

054569087

ABSTRACT:
Novel classes of inhibitors which selectively inhibit the cellular transport of normally transported substances, specifically polyamines are taught which comprise (i) polymers of the transported substance or (ii) protein or polypeptide conjugates of the transported substance. These inhibitors may be used in vitro to assess the effect of the transported substance on cellular functions and in vivo for treating disease conditions involving transport of the particular substance, e.g., a polyamine.

REFERENCES:
patent: 4701521 (1987-10-01), Ryser

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