Polyamine derivatives as antineoplastic agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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564512, A61K 3113, C07C21109

Patent

active

051090244

ABSTRACT:
The present invention relates to certain novel polyamine compounds of the formula: ##STR1## wherein Z is a saturated (C.sub.2 -C.sub.6) alkylene moiety, each R group independently is hydrogen, methyl, ethyl, or n-propyl with the provisos that both R groups cannot be hydrogen and that R is hydrogen or methyl when Z is a branched chain alkylene; or a pharmaceutically acceptable acid addition salt thereof.

REFERENCES:
Edwards, Michael L. et al., J. Med. Chem. 33:1369-1375 (1990).

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