Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1998-05-05
2000-01-25
Mach, D. Margaret M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514169, 514182, 514579, 514613, 514659, 552502, 536 5, 536 61, A61K 31715, A61K 3156
Patent
active
060179066
ABSTRACT:
The present invention relates to methods of preventing or treating an infection or disease caused by an infectious agent. The present invention also relates to the augmentation of the efficacy of existing anti-infective agents by the co-administration of the compounds described herein.
REFERENCES:
patent: 5795870 (1998-08-01), Kahne
patent: 5795885 (1998-08-01), Zasloff
patent: 5834453 (1998-11-01), Regen
Moore, K. S. "Squalamine: An Aminosterol from the Shark", Proc. Nat'l. Acad. Sci. (1993) 90:1354-1358.
Vaara, M. "Agents That Increase the Permeability of the Outer Membrane", Microbil. Rev. (1992) 56:395-411.
Varra, M. "Sentization of Gram-negative Bacteria to Antibiotics and Complement by Non-toxic Oligopeptides", Nature (1983) 303:526-528.
Sandownik, A. et al. "Rapid Construction of a Squalamine Mimic", J. Am. Chem. Soc. (1995) 117:6138-6139.
Bellini, A.M. et al., "Antimicrobial Activity of cholane Compounds: cholic and Deoxycholic Acid Derivatives", Eur. J. Med. Chem (1983) 18(2):185-190.
Bellini, A.M. et al., "Antimicrobial Activity of Cholane Compounds: Cheno and Ursodeoxycholic Acid Derivatives", Eur. J. Med. Chem (1983) 18(2):191-195.
Axelrod Helena R.
Kakarla Ramesh
Kogan Natan A.
Mintz Clifford S.
Sofia Michael J.
Intercardia, Inc.
M. Mach D. Margaret
Villacorta Gilberto M.
LandOfFree
Polyamine conjugates for treatment of infection does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polyamine conjugates for treatment of infection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polyamine conjugates for treatment of infection will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2316044