Polyamine based bonded phase chromatography

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Ion-exchange polymer or process of preparing

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525101, 521 25, 528 10, 528 28, C08D 520, C08F 3008, C08G 7704

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active

045607044

ABSTRACT:
Bonded phase chromatography is disclosed wherein an organosilane reacts with a polyamine to form a support matrix which is attached to the inorganic surface of a support structure. In forming an organic polyamine support matrix, a neutral organosilane is bonded to the inorganic surface with the organosilane having a functional group sufficiently reactive so that an organic amine polymer reacts with the functional group to cause covalent bonding of the organic amine polymer to the inorganic surface. By addition of an organic stationary phase group, the organic polyamine support matrix is formed into any predetermined one of a plurality of types of chromatography supports.

REFERENCES:
patent: 2728743 (1955-12-01), Warrick
patent: 3886080 (1975-05-01), Schucker et al.
patent: 3969261 (1976-07-01), Meiller
patent: 3983299 (1976-09-01), Regnier
patent: 3998985 (1976-12-01), Kitaj
patent: 4291154 (1981-09-01), Blount
patent: 4415631 (1983-11-01), Schutijser

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