Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
2006-12-05
2006-12-05
Desai, Rita J. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
C564S336000
Reexamination Certificate
active
07144920
ABSTRACT:
Novel polyamines, their synthesis and use in pharmacological, cosmetic or agricultural applications are provided. The polyamines induce antizyme production which in turn down regulates both the production of polyamines by omithine decarboxylase (ODC) and the transport of polyamines by its corresponding polyamine transporter. These compounds will preferably enter the cell independent of the polyamine transporter. As drugs, these compounds are used to treat any disease associated with cellular proliferation including but not limited to cancer.
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Aaron Ciechanover et al., &#
Burns Mark R.
Graminski Gerard F.
Connolly Bove & Lodge & Hutz LLP
Desai Rita J.
MediQuest Therapeutics, Inc.
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