Polyamine analog conjugates and quinone conjugates as...

Details Polyamine analog conjugates and quinone conjugates as... Polyamine analog conjugates and quinone conjugates as...

2007-10-09

2007-10-09

Russel, Jeffrey Edwin (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

C514S674000, C564S455000, C564S512000

Reexamination Certificate

active

10970089

ABSTRACT:
Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as compositions comprising these conjugates. Methods of using these conjugates in the treatment of prostate diseases are also provided.

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