Polyamides for nucleic acid delivery

Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...

Reexamination Certificate

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C514S300000, C514S054000, C514S04400A

Reexamination Certificate

active

08034619

ABSTRACT:
The present invention describes reagents and methods for using concatermized double-stranded oligonucleotide molecules (CODN) for transcription factor decoys. In one embodiment, the concatemers consist of a variable number of end-to-end copies of a short dsDNA containing a sequence or sequences that act as transcription factor decoys.

REFERENCES:
patent: 6262033 (2001-07-01), Morishita et al.
Reineke et al. PMSE Preprints, Sep. 2003. 89:53-54.

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