Polyalkylene glycols used for the preparation of peptides

Details Polyalkylene glycols used for the preparation of peptides Polyalkylene glycols used for the preparation of peptides

1974-12-04

1976-06-01

Gotts, Lewis

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352

Patent

active

039608301

ABSTRACT:
A process for the synthesis of peptides in a liquid phase wherein the peptide product, and intermediates in the peptide synthesis, are bound to a polyalkylene glycol polymer and wherein the polymer-bound peptide is separated from the liquid phase, e.g. for purposes of isolation or purification, by crystallizing the polymer-bound peptide.

REFERENCES:
patent: 3502545 (1970-03-01), Westman et al.
patent: 3645852 (1972-02-01), Axen et al.
Bayer et al.: Nature, 237, pp. 512-513, (1972).

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