Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Synthesis of peptides
Reexamination Certificate
2011-05-31
2011-05-31
Ha, Julie (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Synthesis of peptides
C435S068100
Reexamination Certificate
active
07951912
ABSTRACT:
Disclosed is a method of making β-polypeptides. The method includes polymerizing β-lactam-containing monomers in the presence of a base initiator and a co-initiator which is not a metal-containing molecule to yield the product β-polypeptides. Specifically disclosed are methods wherein the base initiator is potassium t-butoxide, lithium bis(trimethylsilyl)amide (LiN(TMS)2), potassium bis(trimethyl-silyl)amide, and sodium ethoxide, and the reaction is carried out in a solvent such as chloroform, dichloromethane, dimethylsulfoxide, or tetrahydrofuran.
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Gellman Samuel H.
Ilker Mehmet F.
Kissounko Denis
Lee Sarah
Stahl Shannon S.
DeWitt Ross & Stevens S.C.
Ha Julie
Leone, Esq. Joseph T.
Wisconsin Alumni Research Foundation
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