Poly(propylene fumarate)

Details Poly(propylene fumarate) Poly(propylene fumarate)

1994-04-28

1998-03-31

Merriam, Andrew E. C.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Processes of preparing a desired or intentional composition...

523114, 523115, 424 7831, 424423, 424549, 528272, C08G 6302, C08K 332, A61F 200

Patent

active

057339511

ABSTRACT:
A novel pathway for the synthesis of poly(propylene fumarate) includes first producing bis-hydroxypropyl fumarate and then its transesterification into poly(propylene fumarate). This synthetic pathway permits production of high molecular weight poly(propylene fumarate) and enables the production of a composite material useful in orthopedic procedures.

REFERENCES:
patent: 4243763 (1981-01-01), Argentar
patent: 4722948 (1988-02-01), Sanderson
patent: 4843112 (1989-06-01), Gerhart et al.
patent: 4888413 (1989-12-01), Domb
patent: 5286763 (1994-02-01), Gerhart et al.
Domb et al., J. Polymer Science, 28:973-985 (1990).
Gerhart et al., J. Orthopedic Research, 4:76-85 (1986).
Gerhart et al., J. Orthopedic Research, 6:585-592 (1988).
Gerhart et al., J. Biomedical Materials Research, 22:1071-1082 (1988).
Gerhart et al., J. Biomedical Materials Research, 23:1-16 (1989).
Goldstein, Journal of Biomechanics, 20:1055-1061 (1987).
Saha & Pal, J. Biomedical Materials Research, 18:435-462 (1984).

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