Chemistry: molecular biology and microbiology – Vector – per se
Patent
1989-11-14
1991-03-05
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Vector, per se
536 27, 435212, 435215, C12N 1558
Patent
active
049977660
ABSTRACT:
Hybrid, third generation, plasminogen activators containing plural, heterologous polypeptide kringles prepared by recombinant DNA techniques as well as the genes coding for the activators. Vectors containing those genes and a method for using the plasminogen activators as thrombolytic agents, are disclosed.
REFERENCES:
patent: 4752581 (1988-06-01), Robinson et al.
patent: 4766075 (1988-08-01), Goeddel et al.
Nelles et al., J. Biol. Chem., vol. 262, pp. 10855-10862, 1987.
Gheysen et al., J. Biol. Chem., vol. 262, pp. 11779-11784, 1987.
Pierard et al., J. Biol. Chem. vol. 262, pp. 11771-11778, 1987.
Hung Paul P.
Kalyan Narender K.
Lee Shaw-guang L.
American Home Products Corporation
Jackson Richard K.
Porta Marianne
Schwartz Richard A.
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