Poly(glycolic acid)/poly(alkylene glycol) block copolymers and m

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – From phenol – phenol ether – or inorganic phenolate

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128 92C, 128335, 1283355, 1283481, 525408, 525450, C08G 6306

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active

044382537

ABSTRACT:
Multiblock copolymers having the following general formula: ##STR1## where R represents alkylene and Ar is an aromatic group, are obtained by transesterification of poly(glycolic acid) and an hydroxyl-ended poly(alkylene glycol) such as poly(oxyethylene) in the presence of a catalyst with the degree of polymerization of the copolymer being increased by the subsequent addition of an aromatic orthocarbonate such as tetra-p-tolyl orthocarbonate. The copolymers find use in the manufacture of surgical articles, particularly absorbable monofilament sutures possessing the desired characteristics of flexibility, resulting in good handling properties, and biodegradability.

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Reed, et al., "Trans. Am. Soc. Artif. Intern. Organs", 1977, p. 109, Biodegradable Elastomeric Biomaterials-Polyethylene Oxide/Polyethylene Terephthalate Copolymers.

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