Poly (ester-anhydrides) and intermediates therefor

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – From carboxylic acid or derivative thereof

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528271, 528354, 528361, 528398, 424 7801, 424426, C08G 6306

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active

057566526

ABSTRACT:
Biodegradable poly(ester-anhydrides) designed to display two-stage degradation profiles are described. The presence of the anhydride linkages allows a relatively rapid decrease in molecular weight, the extent of which is governed by the concentration of the anhydride linkages along the chain, followed by possible dissolution and a slower degradation of the remaining oligomers, the rate of which is governed by the composition of the polyester prepolymers. Methods for the preparation of the poly(ester-anhydrides) and their polyester precursors are also described.

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