Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices
Patent
1995-06-06
1997-11-11
Kight, John
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Matrices
530356, 536 20, 536 552, 514 2, 514 55, 514 62, 424443, 424444, 424484, 424488, C08L 508, C08B 3708, A61K 3173
Patent
active
056861150
ABSTRACT:
The present invention relates to a purified, easily produced poly-.beta.-1.fwdarw.4-N-acetylglucosamine (p-GlcNAc) polysaccharide species useful in collagen copolymers. The p-GlcNAc of the invention is a polymer of high molecular weight whose constituent monosaccharide sugars are attached in a .beta.-1.fwdarw.4 conformation, and which is free of proteins, and substantially free of single amino acids, and other organic and inorganic contaminants. In addition, derivatives and reformulations of p-GlcNAc are described. The present invention further relates to methods for the purification of the p-GlcNAc of the invention from microalgae, preferably diatom, starting sources. Still further, the invention relates to methods for the derivatization and reformulation of the p-GlcNAc. Additionally, the present invention relates to the uses of pure p-GlcNAc, its derivatives, and/or its reformulations.
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Finkielsztein Sergio
Helton Mike
Pariser Ernest R.
Vournakis John N.
Fonda Kathleen Kahler
Kight John
Marine Polymer Technologies Inc.
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