Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1977-12-05
1979-04-24
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 28, 536 27, 424180, C07H 1700, A61K 3170
Patent
active
041513509
ABSTRACT:
The invention relates to copolymers of 5-hydroxycytidylic acid and at least one other polynucleotide selected from cytidylic acid and monomers derived therefrom by bromination. The polymers of the invention are prepared by the bromination of polycytidylic acid and subsequent hydrolysis of the product. The copolymers of the invention demonstrate antiviral properties in vivo.
REFERENCES:
patent: 3935185 (1976-01-01), Hutchinson et al.
Means, G., et al., Biochem. Biophys. Acta, 247, 441 (1971).
Eaton, M., et al., Biochem. Biophys. Acta, 349, 281 (1973).
Eaton Michael A.
Stebbing Nowell
Brown Johnnie R.
G. D. Searle & Co.
Hazel Blondel
McDonnell John J.
Murphy Michael T.
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