Polarized total internal reflection illumination optical...

Details Polarized total internal reflection illumination optical... Polarized total internal reflection illumination optical...

2003-09-18

2009-02-03

Allen, Stephone B (Department: 2872)

Optical: systems and elements

Compound lens system

Microscope

C359S213100, C359S220100

Reexamination Certificate

active

07486440

ABSTRACT:
An illumination system uses rotatable, polarized illumination optics to detect the direction of highly efficient excitation of fluorescent dyes coupled to a sample, or the absorption transition moment, using information on the direction of maximal fluorescence intensity, in which it is possible to detect individual dynamic changes in the internal structure or orientation of an entire protein molecule by coupling a single fluorescent dye molecule to the protein molecule. The polarized total internal reflection illumination optical system by rotary annulus light is also an illumination optical system in which laser beams are introduced into the objective lens of a microscope at the peripheral region by means of the rotatable illumination direction of the laser beams, and is designed to illuminate by the evanescent field that contains only transverse components that are perpendicular to the direction of radiation from the optical axis of the objective lens.

REFERENCES:
patent: 5481384 (1996-01-01), Kramer et al.
patent: 08-122036 (1996-05-01), None
patent: 09-159922 (1997-06-01), None
patent: 2003-131141 (2003-05-01), None
International Search Report mailed on Nov. 18, 2003.

Affiliated with

Also associated with

Rating

Polarized total internal reflection illumination optical... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polarized total internal reflection illumination optical..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polarized total internal reflection illumination optical... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4061603