Polarized light imaging devices and methods

Details Polarized light imaging devices and methods Polarized light imaging devices and methods

2004-03-18

2009-12-01

Casler, Brian (Department: 3737)

Surgery

Diagnostic testing

Detecting nuclear, electromagnetic, or ultrasonic radiation

C600S474000, C600S475000, C600S476000, C600S477000, C600S407000

Reexamination Certificate

active

07627363

ABSTRACT:
The present invention is directed to a novel multi-spectral contrast agent-enhanced polarized light imaging technique that enables rapid imaging of large tissue fields. The imaging device includes a tunable monochromatic light source and a CCD camera. Linear polarizers are placed into both the incident and collected light pathways in order to limit the measurement volume to the superficial tissue layers. To enhance the tumor contrast in the image, aqueous solutions of toluidine blue or methylene blue are topically applied.

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Supplementary European Search Report dated Mar. 9, 2007.

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