Point source biological agent detection system

Details Point source biological agent detection system Point source biological agent detection system

2008-07-29

2008-07-29

Lu, Frank (Department: 1634)

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

C435S283100, C435S287200, C422S050000, C422S068100

Reexamination Certificate

active

07405073

ABSTRACT:
This invention is directed to a method and apparatus using polymerase chain reaction (PCR) technology for collecting air samples and identifying biological agents in the air sample. The apparatus is capable of detecting transient events such asbacillus anthracisin a piece of mail being processed on high-speed mail processing equipment. The system includes apparatus for implementing the following features: particle collection and pre-separation using a collection hood and dry cyclone passive filtration system; continuous particle collection into a liquid sample; automated fluid transfer to a PCR analysis cartridge; and PCR biological identifier apparatus for detecting a bio-agent in a piece of mail following manual transport of the cartridge to the identifier apparatus; retesting of the liquid sample upon various error conditions; confirmation testing upon preliminary positive results; fluid transfer to archive containers at the completion of analysis; and, notification/reporting system to alert designated personnel/organizations upon the occurrence of selected events such as the presence ofbacillus anthracis.

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