Pluripotent embryonic-like stem cells derived from corneal...

Details Pluripotent embryonic-like stem cells derived from corneal... Pluripotent embryonic-like stem cells derived from corneal...

2009-01-16

2011-11-29

Li, Q. Janice (Department: 1633)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S363000, C435S366000, C435S374000, C435S383000, C435S384000

Reexamination Certificate

active

08067233

ABSTRACT:
The present disclosure describes mammalian pluripotent embryonic-like stem cells (ELSCs) isolated from corneal limbal tissue, a non-embryonic tissue. The ELSCs of the present disclosure are capable of proliferating in an in vitro culture, maintain the potential to differentiate into cells of endoderm, mesoderm, and ectoderm lineage in culture, and are capable of forming embryoid-like bodies when placed in suspension culture. Thus, these cells possess multi-lineage differentiation potential and self-renewing capability. ELSCs may be a promising therapeutic tool, and may provide new therapeutic alternatives for various diseases, conditions, and injuries.

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