Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1996-11-15
1999-06-08
Ulm, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530399, 530413, 536 2351, 930120, A61K 3818, C07K 14435, C12N 1518
Patent
active
059104830
ABSTRACT:
The invention relates to a purified growth factor protein which is obtained from Spirometra mansonoides, and a pharmaceutical composition which includes the same. The protein has a molecular weight of 27,500 and an isoelectric point of 4.5. The amino acid sequence has been characterized as well as the DNA sequence which encodes it.
REFERENCES:
patent: 3853833 (1974-12-01), Li
abstract No. 57632p, Phares, C.K., "Isolation by Polyacrylamide Gel Electrophoresis of the Growth Factor From Plerocercoids of the Tapeworm, Spirometra Masonoides", Chemical Abstracts, vol. 80, 1974; Prep. Biochem. 1973 3(4), 375-81.
abstract No. 98:174998v, Friedman, "Characterization of Cobalamin Receptor Sites in Brush-Border Plasma Membranes of the Tapeworm Spirometra Masonoides", Chemical Abstracts, vol. 98, 1983; J. Biol. Chem, 1983, 258(7), 4261-5.
abstract No. 97:124372v, Friedman, "Spirometra Mansonoides: Lectin Analysis of Tegumental Glycopeptides", Chemical Abstracts. vol. 97, 1982; Exp. Parasitol, 1982, 54(1), 93-103.
Phares, "A Method for Solubilization of a Human Growth Hormone Analogue From Plerocercoids of Spirometra Mansonoides", The Journal of Parasitology, vol. 70, No. 5, Oct. 1984, pp. 840-842.
Saovd Christine
The Board of Regents of the University of Nebraska
Ulm John
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