Platinum pharmaceuticals

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536121, C07H 1500, C07H 2300

Patent

active

048959359

ABSTRACT:
Platinum compounds of the formulae: ##STR1## are disclosed. Compositions containing these compounds and methods of using the same in the treatment of tumors are also discussed.

REFERENCES:
patent: 4284579 (1981-08-01), Meischen
patent: 4551524 (1985-11-01), Kidani
patent: 4575550 (1986-03-01), Totani
Cisplatin: Current Status and New Developments, Stephen K. Carter, Academic Press, 1980, pp. 317-431.
O. Gandolfi et al., "Aminomalonato(1,2-diaminocyclohexane)platinum(II)," Inorganica Chimica Acta, vol. 135, pp. 27-31, 1987.
M. P. Hacker et al., "Water-Soluble N-substituted Iminodiacetato(1,2-diaminocyclohexane)-platinum(II) Complexes as Potential Antitumor Agents," Cancer Research, vol. 46, pp. 6250-6254, 1986.
L. A. Zwelling, "Cisplatin and New Platinum Analogs," Cancer Chemotherapy 7, Ch. 8, pp. 105-122, 1985.

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