Platinum derivatives and cancer treatments

Details Platinum derivatives and cancer treatments Platinum derivatives and cancer treatments

1987-08-24

1990-06-26

Garvin, Patrick P.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heavy metal containing doai

514182, 2604045, 260414, 260404, 556137, 552504, A61K 3113, A61K 3116

Patent

active

049372629

ABSTRACT:
Derivatives of platinum group metals, particularly platinum itself, wherein the metal is linked to one or more pharmaceutically acceptable steroid, fatty acid or other lipophilic residues aiding transport of the metal across cell membranes in the body, particularly fatty acid amine or fatty acid amide groups ##STR1## where R is a hydrocarbon group, suitably of 10 to 30 carbon atoms. The derivatives are useful in the treatment of cancer.

REFERENCES:
patent: 4438033 (1984-03-01), Botteghi et al.
patent: 4760155 (1988-07-01), Heffernan et al.

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