Platinum compounds for the irradication of skin blemishes

Details Platinum compounds for the irradication of skin blemishes Platinum compounds for the irradication of skin blemishes

1976-08-04

1981-03-10

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Anti-idiotypic

424287, A61K 3324, A61K 3128

Patent

active

042554179

ABSTRACT:
A method of treating external skin blemishes which comprises applying to the skin an effective amount of a platinum compound having the structures: ##STR1## wherein X and Y are either halogens or the oxygen atoms of a carboxylate bidentete ligand and A and B comprise NH.sub.3 groups or organic amines.
In the octahedral case (Pt valence=IV) Z is either halogens or hydroxyl (OH) groups.

REFERENCES:
patent: 3892790 (1975-07-01), Tobe et al.
patent: 3904663 (1975-09-01), Tobe et al.
patent: 4053587 (1977-10-01), Davidson et al.
Connors et al., Platinum Coordination Complexes in Cancer Chemotherapy, 1974, pp. 26 and 102-104.
Andrewes, Viruses of Vertebrates, 1964, pp. 199-200.
Rosenberg et al., Nature, vol. 222, 4/26/69, pp. 385-386.
Chemical Abstracts 74:108373r, (1971).
Dillaha et al., Chemical Abstracts 66:54195x, (1967).

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