Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heavy metal containing doai
Patent
1987-03-27
1989-09-12
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heavy metal containing doai
A61K 3128
Patent
active
048660922
ABSTRACT:
Novel organic compounds of the formula ##STR1## where R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and alkyl(C.sub.1 -C.sub.6); or R.sub.1 and R.sub.2 taken together are selected from the group consisting of ##STR2## where n is an integer 3-6, ##STR3## where m is an integer 3-6, and ##STR4## and L is selected from the group consisting of --O--, --CH.sub.2 --, ##STR5## and >NR.sub.3 where R.sub.3 is alkyl(C.sub.1 -C.sub.6) or --CH.sub.2 CH.sub.2 OH, which have antineoplastic activity, compositions containing the compounds and methods of using the compounds to treat tumors in mammals.
REFERENCES:
patent: 4164846 (1979-10-01), Kidani et al.
patent: 4203912 (1980-05-01), Hydes et al.
patent: 4225529 (1980-09-01), Hydes et al.
patent: 4230631 (1980-10-01), Hydes et al.
patent: 4250189 (1981-02-01), Hydes et al.
Bitha Panayota
Child Ralph G.
Hlavka Joseph J.
Lin Yang-I
American Cyanamid Company
Goldberg Jerome D.
Jackson H. G.
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