Platinum complex, process for preparing same and antitumor agent

Details Platinum complex, process for preparing same and antitumor agent Platinum complex, process for preparing same and antitumor agent

1989-04-13

1990-12-25

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514184, 549 3, 549210, C07F 1500, A61K 3128

Patent

active

049803476

ABSTRACT:
A platinum complex represented by the formula: ##STR1## where X is ##STR2## wherein R.sup.1 is a (C1-18) alkyl group, a (C1-18)alkenyl group or a group --Z--R.sup.4 in which Z is --CH.dbd.CH-- or a (C1-5)alkylene group, and R.sup.4 is a phenyl group, a hydroxyphenyl group, a (C7-12)alkoxyphenyl group, a halogenophenyl group, a nitrophenyl group, or (C8-13)alkoxycarbonylphenyl group, a cyclohexyl group having a (C1-5)alkyl substituent, ##STR3## R.sup.2 is hydrogen or a (C1-18)alkyl group, R.sup.3 is hydrogen or a (C1-3) alkyl group, R.sup.2 and R.sup.3 are linked together to form a (C2-7)alkylene group; the dotted line indicates that the bond may be either a single bond or a double bond; the chain line indicates a conjugated system; the 1,2-diaminocyclohexane moiety has a cis-, trans-l- or trans-d-configuration; and Y is an anion. This platinum complex is useful in the treatment of tumors.

REFERENCES:
patent: 4661516 (1987-04-01), Brown et al.

Affiliated with

Also associated with

Rating

Platinum complex, process for preparing same and antitumor agent does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Platinum complex, process for preparing same and antitumor agent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Platinum complex, process for preparing same and antitumor agent will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1162866