Organic compounds -- part of the class 532-570 series – Organic compounds – Heavy metal containing
Patent
1986-06-11
1988-07-26
Kight, John
Organic compounds -- part of the class 532-570 series
Organic compounds
Heavy metal containing
556137, 514492, C07F 1500
Patent
active
047601566
ABSTRACT:
A platinum co-ordination compound linkable to a monoclonal antibody by a functional group which forms part of a moiety which stabilises the antibody against in vivo hydrolysis. Also the use of such compounds in the treatment of cancer.
REFERENCES:
patent: 4376782 (1981-03-01), Turkevich et al.
patent: 4410544 (1983-10-01), Berg et al.
patent: 4607114 (1986-08-01), Nakayama et al.
patent: 4614811 (1986-09-01), Gandolfi
Organometallic and Coordination Chemistry of Platinum, 1974 ed, Academic Press, Belluco.
Cleare Michael J.
Heffernan James G.
Picker Donald H.
Draper Garnette D.
Kight John
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