Platinum co-ordination compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Heavy metal containing

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556137, 514492, C07F 1500

Patent

active

047601558

ABSTRACT:
Platinum co-ordination compounds comprising at least one amine ligand and a functional group remotely bonded to the amine ligand, which functional group may be linkable to a monoclonal antibody to provide a moiety which stabilizes the antibody against in vivo hydrolysis.

REFERENCES:
patent: 4372890 (1983-02-01), Yoshikumi et al.
patent: 4500465 (1985-02-01), Amundsen
patent: 4560781 (1985-12-01), Totani et al.
patent: 4577038 (1986-03-01), Totani et al.
patent: 4607114 (1986-08-01), Nakayama
Organometallic and Coordination Chemistry of Platinum, 1974 ed., Academic Press, Belluco.

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