Organic compounds -- part of the class 532-570 series – Organic compounds – Heavy metal containing
Patent
1986-03-21
1987-06-16
Sneed, Helen M. S.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heavy metal containing
536 32, 536 51, 536 63, 536112, 536121, C07F 1500
Patent
active
046737545
ABSTRACT:
Compositions of matter are provided wherein cis-platinum (II) and cis-palladium (II) moieties having amine substituents are bonded to anionic macromolecular entities. These compositions of matter may have improved solubility in the plasma and are effective antitrypanosomal and antitumor agents in mammals. Alternatively, the compositions of matter may be insoluble in water and particularly adapted for in situ implantation into tumerous masses.
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Bernstein Philip
Brown Douglas S.
Smith Gaylord D.
Weller John E.
INCO Alloys International, Inc.
Kenny Raymond J.
Mulligan, Jr. Francis J.
Sneed Helen M. S.
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