Platforms, particularly prostheses, having biologically...

Details Platforms, particularly prostheses, having biologically... Platforms, particularly prostheses, having biologically...

2004-06-18

2010-11-23

Azpuru, Carlos A (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

Reexamination Certificate

active

07838021

ABSTRACT:
The invention relates to the use of extracellular matrix regulators for producing a pharmacologically active covering on a platform or a prosthesis. This covering is of application to endoluminal prostheses, preferably using decorine or a fragment or derivative thereof as cellular matrix inhibitor.

REFERENCES:
patent: 5650389 (1997-07-01), Krumdieck et al.
patent: 6413931 (2002-07-01), Hook et al.
patent: 6579978 (2003-06-01), Renier et al.
patent: 00/40278 (2000-07-01), None
patent: 01/43789 (2001-06-01), None
Fischer et al., “Local expression of bovine decorin by cell-mediated gene transfer reduces neointimal formation after balloon injury in rats”, Circulation Research, vol. 86, No. 6, Mar. 31, 2000, pp. 676-683, XP002315415.
International Search Report of PCT/FR2004/001528, mailed Feb. 15, 2005.

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