Platelet related growth regulator

Details Platelet related growth regulator Platelet related growth regulator

1984-03-23

1986-05-20

Phillips, Delbert R.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

4 to 5 amino acid residues in defined sequence

435240, 435241, 530328, 530326, 530324, 530351, C07K 706, C07K 708, C07K 710, C12N 500, C12N 502

Patent

active

045900035

ABSTRACT:
Polypeptide compositions are provided which inhibit human tumor cell growth. The compositions may be obtained from mammalian blood platelets by selective extraction and purification procedures and are shown to inhibit tumor growth in vitro.

REFERENCES:
patent: 4479896 (1984-10-01), Antoniades
J. Physiol. (1979) 99 (3) pp. 395-406.
Proc. Nat'l. Acad. Sci., 76, (1979) 1809-1813.
Biochim et Biophysica Acta, 560 (1979) 217-241.
Proc. Nat'l. Acad. Sci., 76, 3722-3726 (1979).

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