Platelet membrane microvesicles

Details Platelet membrane microvesicles Platelet membrane microvesicles

1989-04-14

1993-02-09

Stone, Jacqueline

Drug, bio-affecting and body treating compositions

Extract, body fluid, or cellular material of undetermined...

Blood

435236, A61K 3514, C12N 704

Patent

active

051851601

ABSTRACT:
A heat-treated, viral-inactivated platelet membrane microparticle fraction is provided. The microparticles may be prepared from outdated platelets. The microparticle fraction is substantially free of platelet ghosts and may be used as a pharmaceutical preparation in transfusions.

REFERENCES:
patent: 4456590 (1984-06-01), Rubinstein
patent: 4540573 (1985-09-01), Neurath et al.
patent: 4753797 (1988-06-01), Garcez
patent: 4760131 (1988-07-01), Sundomo et al.
patent: 4764463 (1988-08-01), Mason et al.
patent: 4994438 (1991-02-01), Rubinstein
George et al., Biol. Abstracts, vol. 82:69920 (1986).
McGill et al., Transfusion Abstract (1983) p. 414.
McGill et al., J. Lab. Clin. Med. 109:127 (1987).
Klein et al., Am. J. Pediat. 49:517 (1956).
Alkjaersig et al., Am. J. Physiol. 1810, 304-307 (1955).
Wu et al., Thromb. Res. 11:581 (1977).
Sandberg et al., Biochem. J. 203, 303-311 (1982).
Sandberg et al., Thromb. Res. 18:871 (1980).
Nichols et al., Blood 68 (Suppl. 1): 300a (1986).
Tullis et al., Blood 14:459 (1959).
Chao et al., Thromb. Haem. 47:459 (1982).
Chao et al., Brit. J. Haematol. 39:177 (1978).
Kahn et al., Blood 66:1 (1985).
Hjort et al., Proc. Soc. Exp. Biol. Med. 102:31 (1959).
Firkin et al., Blood 15:388 (1960).
Jackson et al., J. Clin. Invest. 38:1689-1697 (1959).
Zucker, J. Lab. Clin. Med. 109:111 (1987).
Stefanini et al., Clin. Res. Proc. 5:151-152 (1957).
Walsh et al., in Hemostasis and Thrombosis, (1987), p. 689.
George et al., Blood, vol. 68, No. 1 (1986) pp. 307-309.
Schilt, U., Overview of Viruses Relevant to Blood Transfusion, "Virus Inactivation in Plasma Products".
Heimburger, N., and Karges, H. E., Strategies to Produce Virus-Safe Blood Derivates. "Virus Inactivation in Plasma Products".
Piszkiewicz, D., Thomas, W., Lieu, M. Y., Tse, D., and Sarno, L., Virus Inactivation by Heat Treatment of Lyophilized Coagulation Factor Concentrates, "Inactivation in Plasma Products".
Winkelman, L., Feldman, P. A., and Evans, D. R., Severe Heat Treatment of Lyophilised Coagulation Factors, "Virus Inactivation Plasma Products".

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