Platelet membrane glycoprotein F11 and polypeptide fragments the

Details Platelet membrane glycoprotein F11 and polypeptide fragments the Platelet membrane glycoprotein F11 and polypeptide fragments the

1994-11-17

1997-09-09

Walsh, Stephen

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530395, 530380, A61K 3816, C07K 14705

Patent

active

056657013

ABSTRACT:
The subject invention provides a platelet membrane glycoprotein, designated F11, which serves as a receptor for the monoclonal antibody M.Ab.F11. The purified platelet membrane glycoprotein has a deglycosylated molecular weight of about 29 kD. A partial sequence for the glycoprotein is also provided, as well as expression vectors and systems for producing the glycoprotein or fragments thereof.

REFERENCES:
Kornecki et al., "Activation of Human Platelets by a Stimulatory Monoclonal Antibody," J Biol Chem 265(17):10042-10048 (Jun. 15, 1990).

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