Platelet glycoprotein V gene and uses

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 231, 536 241, 435 6, 4352523, 435325, C12N 121, C12N 510, C12N 1512

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active

060050896

ABSTRACT:
This invention relates to the glycoprotein v gene. Specifically, this invention discloses the sequence and structure of the glycoprotein v gene and the amino acid sequence of the glycoprotein v polypeptide. In addition, the evolutionary relationship of the glycoprotein v gene with other glycoproteins is described and several uses of the isolated glycoprotein v gene are shown.

REFERENCES:
Hickey et al., Sept. 1993. PNAS USA: 90: 8327-8331.
Lanza et al. 1993. J. Biol. Chem. 268: 20801-20807.
Sambrook et al. Molecular Cloning: A Laboratory Manual (2nd Ed.), vol. 1-3, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1989.
Bowie et al., 1990, Science 247:1306-1310.
Wicki et al. 1989. Thromb. Haemostas. 61:448-453, 1989
Modderman et al. 1992. J. Biol. Chem. 267:364-369, 1992.
Berndt et al. 1981. J. Biol. Chem. 256:59-65, 1992.
Bienz et al. 1986. Blood 68:720-725, 1986.
Sambrook et al. Molecular Cloning: A Laboratory Manual (2nd ed.)., vol. 1-3, Cold Spring Hrbor Laboratroy, Cold Spring Harbor, NY 1989.
Uhlen, M. et al.: "Gene fusion vectors based on the gene for staphylococcal protein A"; Gene; 1993; vol. 23, pp. 369-378.

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