Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1997-10-09
2000-02-22
Chin, Christopher L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
422 57, 435 79, 435 792, 435 793, 435 794, 435 13, 4352872, 4352879, 435970, 436514, 436524, 436528, 436531, 436534, 436536, 436 87, 436169, G01N 3353, G01N 33536, G01N 33543
Patent
active
060279044
ABSTRACT:
Methods of calculating the platelet count of an individual, by measuring the amount of a released platelet granule protein of interest in a sample of whole blood or of platelet-rich plasma from the individual, are described. The platelet granule protein of interest is either thrombospondin or .beta.-thromboglobulin. The amount of released platelet granule protein of interest in the whole blood sample or platelet-rich plasma sample is measured using an enzyme-linked immunosorbent assay; radioimmunoassay; sandwich assay; a quantitative immunochromatographic assay; or non-solid phase nephelometry. The platelet count is directly related to the amount of released platelet granule protein of interest in the sample, and can be determined from the amount of platelet granule protein of interest that is released from a known number of platelets.
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Brooks Donald Elliott
Devine Dana Virginia
Chin Christopher L.
Grun James L.
University of British Columbia
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