Platelet collection system

Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...

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210637, 210652, 21032169, B01D 1300

Patent

active

048000221

ABSTRACT:
A system is provided for collecting platelets. Whole blood is removed from a patient 10 and directed to a hemoconcentrator 22 having a blood inlet 24, a blood outlet 26, a blood passage communicating with the blood inlet and blood outlet, an ultrafiltrate outlet 28 and a membrane separating the blood passage from the ultrafiltrate outlet. The blood is passed through the blood passage of the hemoconcentrator while a negative pressure is adapted to the ultrafiltrate outlet. In this manner, the platelets concentrate on the membrane wall. After a selected period of time, the application of the negative pressure is terminated to the ultrafiltrate outlet, and the concentrated platelets from the hemoconcentrator are flushed and directed to a platelet collection container 44. In one embodiment, the flushing solution comprises the patient's blood that is directed via the blood inlet through the blood passage while in another embodiment, the patient's blood is diverted and a saline solution is used as the flush. During the flush, a positive pressure may be applied to the ultrafiltrate outlet of the hemoconcentrator.

REFERENCES:
patent: Re31688 (1984-09-01), Popovich et al.
patent: 3399135 (1968-08-01), Conley, Jr. et al.
patent: 4409106 (1983-11-01), Furuta et al.
patent: 4424132 (1984-01-01), Iriguchi
patent: 4579662 (1986-04-01), Jonsson
patent: 4648866 (1987-03-01), Malbrancq et al.
patent: 4655742 (1987-04-01), Vantard

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