Platelet aggregation inhibitory agents and intermediate therefor

Details Platelet aggregation inhibitory agents and intermediate therefor Platelet aggregation inhibitory agents and intermediate therefor

1988-10-05

1991-02-19

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544365, A61K 31495, C07D40114

Patent

active

049944622

ABSTRACT:
This invention relates to certain N,N'-bis(nipecotyl)piperazines and their use as platelet aggregation inhibtory agents.

REFERENCES:
patent: 3786058 (1974-01-01), Edwards
patent: 3932418 (1976-01-01), Janssens et al.
patent: 4443450 (1984-04-01), Lasslo et al.
Lasslo et al. J. Org. Chem., (1956), 21, 958-960.
Lasslo, et al., J. Org. Chem., (1957), 22, 837-838.
Qunitana, et al., J. Pharm. Sci., (1963), 52, 1186-1188.
Beasley et al. J. Med. Chem. (1964), 7, 698-701.
Quintana et al., J. Pharm Sci., (1965), 54, 785-787.
Quintana et al., J. Med. Chem., (1967), 10, 1178-1180.
Ross, J. Med. Chem. (1967), 10, 257-259.
Mendelbaum et al., Adv. Mass Spectrum, (1980), 8A, 828-831.
Grudzinski, Lodz, Towarz, Nauk, Soc. Sci Lodziensis Acta. Chin. (1962), 8, 105-118.
Newkome, et al., J. Org. Chem., (1980), 45, 629-632.
Bald, Chemica Scipta (1979), 13, 47.
Sperber, et al., J. Am. Chem. Soc., (1950), 72, 2012-2015.
Purcell, BioChimica, Biophys. Acta., (1965), 105, 201-204.
Mathison, et al., J. Med. Chem. (1969), 12, 928-931.
Stanley et al., J. Med. Chem. (1974), 17, 8-12.
Kier, J. Med Chem., (1975), 18, 1272-1274.
Quintana et al. "Biophysical J." vol. 33 (1982) pp. 130-133.
Qunitana et al. "Chem-Biol Interactions" (vol. 38) (1982) pp. 135-144.
Quintana et al "Thrombosis Research" (vol. 24) pp. 379-399 (1981).

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