Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-06-06
2006-06-06
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S285000
Reexamination Certificate
active
07056926
ABSTRACT:
Novel compounds of formulae (I) to (VIII), which more particularly include sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylsulfonamide derivatives which are effective platelet ADP receptor inhibitors. These derivatives may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of cardiovascular diseases, particularly those diseases related to thrombosis. The invention also relates to a method for preventing or treating thrombosis in a mammal comprising the step of administering a therapeutically effective amount of a compound of formulae (I) to (VIII), or a pharmaceutically acceptable salt thereof.
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Plotnikova et al., “Arenesulfonamides. LXXX. Aroylarenesulfonamides”. Database CA Online! Chemical Abstracts Service, Columbus, OH, US, retrieved from STN Database Accession No. 82:139564 XP002215531, abstract, &Vopr. Khim. Khim. Tekhnol.(1974), 33, 20-5.
Huang Wolin
Kane-Maguire Kim A.
Marlowe Charles K.
Scarborough Robert M.
Kifle Bruck
Portola Pharmaceuticals Inc.
Townsend and Townsend / and Crew LLP
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