Platelet ADP receptor inhibitors

Details Platelet ADP receptor inhibitors Platelet ADP receptor inhibitors

2006-04-04

2006-04-04

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S465000

Reexamination Certificate

active

07022731

ABSTRACT:
Novel compounds of formula (I) to (VI), which more particularly include sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylsulfonamide derivatives which are effective platelet ADP receptor inhibitors. These derivatives may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of cardiovascular diseases, particularly those diseases related to thrombosis. The invention also relates to a method for preventing or treating thrombosis in a mammal comprising the step of administering a therapeutically effective amount of a compound of formulae (I)–(VI), or a pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 3847925 (1974-11-01), Beregi et al.
patent: 5475025 (1995-12-01), Tjoeng et al.
patent: WO 94/21602 (1994-07-01), None
patent: WO 94/19341 (1994-09-01), None
patent: WO 99/36425 (1999-07-01), None

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