Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-12-05
1996-01-23
Dentz, Bernard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514394, 546118, 5483021, 5483051, A61K 31435, C07D47104
Patent
active
054865255
ABSTRACT:
The present invention relates to compounds of formula ##STR1## and the pharmaceutically acceptable salts thereof which are potent antagonists of PAF and are useful in the treatment of PAF-related disorders including asthma, shock, respiratory distress syndrome, acute inflammation, transplanted organ rejection, gastrointestinal ulceration, allergic skin diseases, delayed cellular immunity, parturition, fetal lung maturation, and cellular differentiation.
REFERENCES:
Chem. Abstr., 96:11505t (1992).
Chem. Abstr., 102: 93257b (1985).
Chem. Abstr., 108: 48713k (1988).
Chem. Abstr., 111: 150783g (1989).
Chem. Abstr., 113: 6344p (1990).
Carrera, Jr. George M.
Curtin Michael L.
Davidsen Steven K.
Garland Robert B.
Heyman H. Robin
Abbott Laboratories
Dentz Bernard
Janssen Jerry F.
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