Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-05-03
1992-09-22
Fan, Jane T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514343, 514336, 546280, 546281, 546284, C07D41704, A61K 3144
Patent
active
051497042
ABSTRACT:
Benzoylphenyl derivatives of 2-(3-pyridinyl)-3-alkyl-4-thiazolidinecarboxamide, 2-(3-pyridinyl)-thiazolid-4-ylacetamide, 2-(3-pyridinyl)-4-dithiolanecarboxamide or 2-(3-pyridinyl)dithiolan-4-yl]urea-group are potent inhibitors of PAF and are useful in the treatment of PAF-related disorders including anaphylactic shock, respiratory distress syndrome, acute inflammation, delayed cellular immunity, parturtition, fetal lung maturation, and cellular differentiation.
REFERENCES:
patent: 4786645 (1988-11-01), Fabre et al.
patent: 4940709 (1990-07-01), Shimazaki et al.
patent: 4948795 (1990-08-01), Mase et al.
Davidsen Steven K.
Guinn Denise E.
Martin Michael B.
Phillips James G.
Steinman Douglas H.
Abbott Laboratories
Fan Jane T.
Janssen Jerry F.
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