Plastin isoforms and their uses

Details Plastin isoforms and their uses Plastin isoforms and their uses

1991-01-10

1994-11-01

Fleisher, Mindy B.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 78, 536 235, 536 243, 536 2431, 530324, 530350, 530380, C12Q 168, C07H 2104, C07K 1300, G01N 3353

Patent

active

053607155

ABSTRACT:
A method and reagents are provided for determining whether a human cell is a hemopoietic cell and whether a human tissue cell is in a neoplastic state. Human cells which express only leukocyte-plastin (l-plastin) are hemopoietic cells and human cells which express both l-plastin and tissue-plastin (t-plastin) are neoplastic. The method can be performed using isoform-specific plastin nucleotide probes or isoform-specific anti-plastin antibodies.

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